#1 Doctor recommended anti-wrinkle serum from New Zealand

World's first medically-proven, fast acting, all natural, anti-wrinkle, skin serum.

No toxins. No needles.
Real tests. Real people.

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“Our clinical trial shows long-term benefits of consistent, continued use of NO-TOX®”

How To Apply



Application depends on your skin type and the results you are seeking to achieve. NO-TOX® has been specially tested and formulated to work with ALL skin tones and skin types - normal, oily and combination skin types. But, essentially, it's a topical application (no needles) where you apply a few drops to the areas of skin you want to treat.

To REDUCE lines and wrinkles

Apply 2-3 drops twice daily and gently smoothe into your lines and wrinkles. Avoid getting product into your eyes. If any serum is left on your fingers, pat it onto surrounding areas gently.

As a skin super-serum to PREVENT signs of aging

NO-TOX® can also work as an anti-aging super-serum. If you are not concerned about a specific area but want a general anti-aging effect, then NO-TOX® can be applied once daily, before bedtime after cleaning your face. Gently apply 2-3 drops onto your fingers and smoothe onto cheeks. 2-3 drops will suffice for each cheek, or side of neck. If any serum is left on your fingers, pat it onto the areas you have treated.

Can NO-TOX® be used with other skin products?

Yes, however there are a few points to remember.

1. Allow NO-TOX® to dry fully and wait for 10 minutes before applying any other product.

2. While NO-TOX® is mostly plant- and plankton-based, it contains the trace mineral copper which helps assemble the amino acids needed to produce collagen. Copper, when outside the cell inactivates vitamin C. Therefore, if you are using a vitamin C serum, AVOID using it at the same time and make sure it is used at a different time of the day, several hours apart.

3. Dr Paul’s unique formulation of NO-TOX® contains hyaluronic acid (HA) that is easily absorbed. Unlike some other HA serums where you have to apply water to skin first to help absorption, there is NO need to do that.

Can NO-TOX® cause skin sensitivity?

Because NO-TOX® contains hyaluronic acid (HA) some people may develop skin irritation. Studies in medical journals show that this happens in less than 0.1% of the time. In our clinical trial, NONE of the participants reported any side effects. In most cases this settles down with time, but if it persists you may have to discontinue use.